:root{--paper: #f6f4ef;--paper-2: #fffefb;--ink: #1b2024;--ink-soft: #3c454c;--muted: #6b7680;--line: #ddd7ca;--line-strong: #c9c2b2;--accent: #0d5c54;--accent-ink: #0a4842;--accent-wash: #0d5c5410;--warn-ink: #7a5200;--warn-bg: #fbf3dd;--warn-line: #e6d29a;--danger: #8f2d2d;--radius: 10px;--radius-sm: 7px;--shadow: 0 1px 2px rgba(27, 32, 36, .04), 0 8px 28px rgba(27, 32, 36, .06);--serif: "Newsreader", Georgia, serif;--sans: "IBM Plex Sans", system-ui, sans-serif}*{box-sizing:border-box}html,body,#root{height:100%}body{margin:0;font-family:var(--sans);background:var(--paper);color:var(--ink);-webkit-font-smoothing:antialiased;text-rendering:optimizeLegibility}h1,h2,h3{font-family:var(--serif);font-weight:500;letter-spacing:-.01em}a{color:var(--accent);text-decoration:none}a:hover{text-decoration:underline}.btn{font-family:var(--sans);font-size:.95rem;font-weight:500;padding:.7rem 1.25rem;border-radius:var(--radius-sm);border:1px solid transparent;cursor:pointer;transition:background .15s ease,border-color .15s ease,transform .05s ease}.btn:active{transform:translateY(1px)}.btn-primary{background:var(--accent);color:#fff}.btn-primary:hover{background:var(--accent-ink)}.btn-primary:disabled{background:var(--line-strong);cursor:not-allowed}.btn-ghost{background:transparent;color:var(--ink-soft);border-color:var(--line)}.btn-ghost:hover{background:var(--accent-wash)}.field{display:flex;flex-direction:column;gap:.35rem}.field label{font-size:.82rem;color:var(--muted);font-weight:500}.input{font-family:var(--sans);font-size:.95rem;padding:.65rem .8rem;border:1px solid var(--line-strong);border-radius:var(--radius-sm);background:var(--paper-2);color:var(--ink);transition:border-color .15s ease,box-shadow .15s ease}.input:focus{outline:none;border-color:var(--accent);box-shadow:0 0 0 3px var(--accent-wash)}.card{background:var(--paper-2);border:1px solid var(--line);border-radius:var(--radius);box-shadow:var(--shadow)}.kvkk-banner{display:flex;gap:.6rem;align-items:flex-start;background:var(--warn-bg);border:1px solid var(--warn-line);color:var(--warn-ink);border-radius:var(--radius-sm);padding:.7rem .9rem;font-size:.86rem;line-height:1.45}.kvkk-banner .icon{flex:0 0 auto;font-size:1rem;line-height:1.3}.error-text{color:var(--danger);font-size:.85rem;min-height:1.1rem}.topbar{display:flex;align-items:center;justify-content:space-between;padding:.85rem 1.5rem;border-bottom:1px solid var(--line);background:var(--paper-2)}.wordmark{font-family:var(--serif);font-size:1.15rem;font-weight:600}.wordmark .dot{color:var(--accent)}.wordmark.on-dark .dot{color:#7ad2c4}.section-title{font-family:var(--serif);font-size:1.05rem;font-weight:600;color:var(--ink);margin:0 0 .75rem;padding-bottom:.4rem;border-bottom:1px solid var(--line)}.row{display:flex;gap:1rem;flex-wrap:wrap}.variant-block{background:var(--paper-2);border:1px solid var(--line);border-radius:var(--radius);padding:1rem 1.1rem;margin-bottom:1rem;box-shadow:var(--shadow)}.variant-head{display:flex;align-items:center;justify-content:space-between;margin-bottom:.6rem}.variant-title{font-weight:600;font-size:.92rem;color:var(--accent-ink)}.icon-btn{border:1px solid var(--line);background:transparent;color:var(--muted);width:26px;height:26px;border-radius:6px;cursor:pointer;line-height:1}.icon-btn:hover{color:var(--danger);border-color:var(--danger)}.chips{display:flex;gap:.4rem;flex-wrap:wrap}.chip{font-family:var(--sans);font-size:.78rem;padding:.3rem .6rem;border-radius:999px;border:1px solid var(--line-strong);background:var(--paper);color:var(--ink-soft);cursor:pointer}.chip:hover{background:var(--accent-wash);border-color:var(--accent);color:var(--accent-ink)}.field-grid{display:grid;grid-template-columns:repeat(auto-fill,minmax(150px,1fr));gap:.75rem;margin-top:.9rem}.field-grid select.input{-webkit-appearance:none;-moz-appearance:none;appearance:none}textarea.input{resize:vertical;font-family:var(--sans)}.variant-progress{border:1px solid var(--line);border-radius:var(--radius-sm);padding:.75rem .9rem;margin-bottom:.75rem;background:var(--paper)}.variant-progress:last-child{margin-bottom:0}.variant-progress-head{font-weight:600;font-size:.88rem;color:var(--ink);margin-bottom:.5rem}.variant-progress-decision{color:var(--accent-ink);font-weight:500}.step-row{display:flex;align-items:center;gap:.55rem;font-size:.85rem;padding:.2rem 0;color:var(--muted)}.step-mark{width:1.1rem;text-align:center;font-size:.9rem;line-height:1}.step-pending .step-mark{color:var(--line-strong)}.step-active{color:var(--ink)}.step-active .step-mark{color:var(--accent);animation:pulse 1.1s ease-in-out infinite}.step-done{color:var(--ink-soft)}.step-done .step-mark{color:var(--accent)}.step-failed,.step-failed .step-mark{color:var(--danger)}@keyframes pulse{0%,to{opacity:1}50%{opacity:.35}}.badge{display:inline-block;font-size:.78rem;font-weight:600;padding:.2rem .55rem;border-radius:999px;border:1px solid transparent}.badge-path{background:#f6dede;color:#8f2d2d;border-color:#e3b4b4}.badge-vus{background:var(--warn-bg);color:var(--warn-ink);border-color:var(--warn-line)}.badge-benign,.badge-green{background:#dceee6;color:#1d6b4f;border-color:#b4dcc9}.badge-yellow{background:var(--warn-bg);color:var(--warn-ink);border-color:var(--warn-line)}.badge-purple{background:#e9e2f3;color:#5a3d86;border-color:#cdbce6}.badge-blue{background:#dde8f3;color:#2a5685;border-color:#b6cce4}.badge-red{background:#f6dede;color:#8f2d2d;border-color:#e3b4b4}.chat-card{padding:1.25rem}.chat-log{display:flex;flex-direction:column;gap:.75rem;max-height:480px;overflow-y:auto;padding:.25rem;margin-bottom:.9rem}.chat-bubble{max-width:85%;padding:.7rem .9rem;border-radius:var(--radius)}.chat-clinician{align-self:flex-end;background:var(--accent-wash);border:1px solid var(--line-strong)}.chat-assistant{align-self:flex-start;background:var(--paper);border:1px solid var(--line)}.chat-text{white-space:pre-wrap;line-height:1.5;font-size:.9rem}.chat-phi-warn{color:var(--warn-ink);font-size:.82rem;margin-bottom:.4rem}.chat-badges,.chat-warnings{display:flex;gap:.35rem;flex-wrap:wrap;margin-top:.6rem}.chat-citations{margin-top:.7rem;border-top:1px solid var(--line);padding-top:.6rem}.chat-citations-head{font-size:.78rem;color:var(--muted);font-weight:600;margin-bottom:.4rem}.chat-citation{font-size:.82rem;margin-bottom:.3rem;display:flex;align-items:center;gap:.3rem;flex-wrap:wrap}.chat-citation-title{color:var(--ink-soft)}.chat-status{display:flex;align-items:center;gap:.5rem;flex-wrap:wrap;color:var(--muted);font-size:.85rem}.chat-spinner{color:var(--accent);animation:pulse 1.1s ease-in-out infinite}.chat-live-sources{display:inline-flex;gap:.3rem;flex-wrap:wrap}.chat-input-row{display:flex;gap:.6rem;align-items:flex-end}.chat-input-row textarea{flex:1}.decision-chips{display:flex;gap:.6rem;flex-wrap:wrap;margin-bottom:1rem}.decision-chip{border:1px solid var(--line);border-radius:var(--radius-sm);padding:.6rem .75rem;background:var(--paper-2);min-width:140px}.decision-chip-gene{font-weight:600;font-size:.9rem;margin-bottom:.35rem}.decision-chip-codes{font-size:.74rem;color:var(--muted);margin-top:.35rem}.report-head{display:flex;align-items:flex-start;justify-content:space-between;gap:1rem;margin-bottom:1rem}.report-actions{display:flex;gap:.6rem;margin-bottom:.75rem}.report-frame{width:100%;height:70vh;border:1px solid var(--line);border-radius:var(--radius);background:#fff}.modal-overlay{position:fixed;top:0;right:0;bottom:0;left:0;background:#1b20246b;display:flex;align-items:center;justify-content:center;padding:1.5rem;z-index:50}.modal{max-width:520px;padding:1.75rem}